Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319248 | 0.80 | ADRA2C (0.35) | KDM4ECHRM2MAPTHTTGAA | |
| SCHEMBL3073595 | 0.78 | CHRM2 (0.62) | KDM4EGLACHRM2GBA1MAPT | |
| SCHEMBL7733811 | 0.77 | GBA1 (0.54) | KDM4EGLACHRM2GBA1HTT | |
| SCHEMBL11142854 | 0.76 | TDP1 (0.54) | KDM4EGLACHRM2GBA1HTT | |
| SCHEMBL6156472 | 0.76 | KDM4E (0.57) | KDM4EGLAMAPTHTTMAPK1 | |
| SCHEMBL8470228 | 0.75 | ALDH1A1 (0.55) | KDM4EGLAGBA1MAPK1TSHR | |
| SCHEMBL27764590 | 0.73 | APP (0.42) | KDM4EMAPTHTTMAPK1ALDH1A1 | |
| SCHEMBL11142847 | 0.72 | KDM4E (0.51) | KDM4EGLACHRM2GBA1MAPT | |
| SCHEMBL3186346 | 0.72 | KDM4E (0.50) | KDM4EGLAGBA1MAPTHTT | |
| SCHEMBL7733793 | 0.71 | KDM4E (0.43) | KDM4EGLACHRM2GBA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394829-A | Composition for the oxidative dyeing of keratin fibers and method for using such a composition | PROCTER & GAMBLE (US) | 2009-03-25 | — | — | CN | claimed |
| CN-101394829-A | Composition for the oxidative dyeing of keratin fibers and method for using such a composition | PROCTER & GAMBLE (US) | 2009-03-25 | — | — | CN | disclosed |