Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996050 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNAKMT2AOPRM1SMN1; SMN2 | |
| SCHEMBL4629636 | 0.88 | LMNA (0.54) | ALDH1A1LMNAKMT2ASMN1; SMN2MTNR1A | |
| SCHEMBL4629634 | 0.88 | LMNA (0.54) | ALDH1A1LMNAKMT2ASMN1; SMN2MTNR1A | |
| SCHEMBL5440679 | 0.88 | LMNA (0.54) | ALDH1A1LMNAKMT2ASMN1; SMN2MTNR1A | |
| SCHEMBL186238 | 0.81 | LMNA (0.61) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL186416 | 0.81 | LMNA (0.61) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL186230 | 0.81 | LMNA (0.61) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL607611 | 0.81 | RIPK1 (0.61) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8582093 | 0.81 | RIPK1 (0.61) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL607610 | 0.81 | RIPK1 (0.61) | LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809824-B2 | CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-11-07 | — | — | US | disclosed |
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |