Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163205 | 0.84 | CA2 (0.52) | CA2CA4HTR2AHSD17B10TPMT | |
| SCHEMBL3759267 | 0.84 | ALDH1A1 (0.44) | PTGS2HSD17B10TPMTALDH1A1KDM4E | |
| SCHEMBL30407976 | 0.78 | CA2 (0.46) | CA2CA4HTR2AHSD17B10TPMT | |
| SCHEMBL2415199 | 0.78 | CA2 (0.46) | CA2CA4HSD17B10TPMTALDH1A1 | |
| SCHEMBL4355782 | 0.78 | CA2 (0.46) | CA2CA4HTR2AHSD17B10TPMT | |
| SCHEMBL31015937 | 0.78 | PTGS2 (0.37) | PTGS2TPMTALDH1A1KDM4EGAA | |
| SCHEMBL1223114 | 0.78 | PTGS2 (0.37) | PTGS2TPMTALDH1A1KDM4EGAA | |
| SCHEMBL12269187 | 0.77 | CA2 (0.45) | CA2CA4HTR2AHSD17B10TPMT | |
| SCHEMBL10209878 | 0.77 | TSHR (0.50) | CA2CA4HTR2APTGS2POLB | |
| SCHEMBL14217767 | 0.77 | CA2 (0.45) | CA2CA4HTR2AHSD17B10TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2975040-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | Sagami Chemical Research Institute (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014142307-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | 公益財団法人相模中央化学研究所 (JP) | 2014-09-18 | — | — | WO | disclosed |
| CN-1127457-C | Process for electrophilic aromatic substitution | BROMINE COMPOUNDS LTD (IL) | 2003-11-12 | — | — | CN | disclosed |
| US-6399835-B1 | ALKYLATION, HALOGENATION USING AQUEOUS SOLUTION OF ZINC HALIDE | BROMINE COMPOUNDS LTD. (IL) | 2002-06-04 | — | — | US | disclosed |
| CN-1280555-A | Process for electrophilic aromatic substitution | BROMINE COMPOUNDS LTD (IL) | 2001-01-17 | — | — | CN | disclosed |
| EP-1032549-A1 | PROCESS FOR ELECTROPHILIC AROMATIC SUBSTITUTION | Bromine Compounds Ltd. (IL) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999019275-A1 | PROCESS FOR ELECTROPHILIC AROMATIC SUBSTITUTION | BROMINE COMPOUNDS LTD. (IL) | 1999-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | CA2 1003/4885CA4 969/4885HTR2A 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.