Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.57 |
| ▸ | PDE4A | P27815 | 5/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590778 | 0.85 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL31619157 | 0.85 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL7326510 | 0.83 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL7326505 | 0.83 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL70835 | 0.82 | ALDH1A1 (0.64) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL29808190 | 0.82 | ALDH1A1 (0.64) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL7560477 | 0.82 | ALDH1A1 (0.64) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL1389060 | 0.82 | ALDH1A1 (0.68) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL13677859 | 0.82 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL8067384 | 0.82 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4CPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |