Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732746 | 0.93 | CCR5 (0.49) | CCR5 | |
| SCHEMBL7730814 | 0.89 | CCR5 (0.53) | CCR5 | |
| SCHEMBL7730605 | 0.89 | CCR5 (0.58) | CCR5 | |
| SCHEMBL7723288 | 0.82 | CCR5 (0.52) | CCR5 | |
| SCHEMBL7723337 | 0.82 | CCR5 (0.51) | CCR5 | |
| SCHEMBL7736194 | 0.79 | CCR5 (0.52) | CCR5 | |
| SCHEMBL7735876 | 0.74 | CCR5 (0.63) | CCR5 | |
| SCHEMBL7644917 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL7984392 | 0.68 | CCR5 (1.00) | CCR5 | |
| SCHEMBL7984390 | 0.68 | CCR5 (1.00) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |