SCHEMBL7733989

SCHEMBL7733989

CCCCCOc1ccc(CCCC(=O)O)cc1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.56
THRB P10828 1/20 0.56
RXRA P19793 1/20 0.49
PTPN11 Q06124 4/20 0.48
PTPN1 P18031 1/20 0.47
PTPN6 P29350 1/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 3/20 0.47
PPARA Q07869 3/20 0.47
CYP1A2 P05177 1/20 0.47
LTB4R Q15722 1/20 0.47
KDM4E B2RXH2 1/20 0.46
SLC6A9 P48067 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
PTGER1 P34995 1/20 0.46
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724925 0.96 THRA (0.52) THRATHRBRXRAPPARGPPARD
SCHEMBL7734086 0.94 THRA (0.57) THRATHRBRXRAPTPN11PTPN1
SCHEMBL8984893 0.91 RXRA (0.56) THRATHRBRXRAPTPN11PTPN1
SCHEMBL7725029 0.91 CYP1A2 (0.52) PPARGPPARDPPARACYP1A2SLC6A9
SCHEMBL7734788 0.90 RXRA (0.53) THRATHRBRXRAPPARGPPARD
SCHEMBL7735866 0.90 CYP1A2 (0.49) THRATHRBPPARGPPARDPPARA
SCHEMBL7724415 0.90 CYP1A2 (0.51) PPARGPPARDPPARACYP1A2SLC6A9
SCHEMBL7737650 0.90 THRA (0.53) THRATHRBPTPN11PTPN1PPARG
SCHEMBL7734076 0.89 CYP1A2 (0.48) THRATHRBPPARGPPARDPPARA
SCHEMBL7735325 0.88 CYP1A2 (0.47) THRATHRBCYP1A2LTB4RSLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN claimed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US claimed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN claimed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP claimed
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed