SCHEMBL7724925

SCHEMBL7724925

CCCCOc1ccc(CCCC(=O)O)cc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
PPARG P37231 3/20 0.50
PPARD Q03181 3/20 0.50
PPARA Q07869 3/20 0.50
CYP1A2 P05177 2/20 0.48
RXRA P19793 1/20 0.47
KDM4E B2RXH2 1/20 0.47
SLC6A9 P48067 1/20 0.47
PTGDR2 Q9Y5Y4 2/20 0.47
FFAR1 O14842 3/20 0.46
FFAR4 Q5NUL3 3/20 0.46
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
PTGER1 P34995 1/20 0.46
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HDAC3 O15379 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733989 0.96 THRA (0.56) THRATHRBPPARGPPARDPPARA
SCHEMBL7734788 0.94 RXRA (0.53) THRATHRBPPARGPPARDPPARA
SCHEMBL7725029 0.92 CYP1A2 (0.52) PPARGPPARDPPARACYP1A2SLC6A9
SCHEMBL7737444 0.91 THRA (0.51) THRATHRBPPARGPPARDPPARA
SCHEMBL7724415 0.91 CYP1A2 (0.51) PPARGPPARDPPARACYP1A2SLC6A9
SCHEMBL7734086 0.90 THRA (0.57) THRATHRBPPARGPPARDPPARA
SCHEMBL7737515 0.89 THRA (0.49) THRATHRBPPARGPPARDPPARA
SCHEMBL7735866 0.89 CYP1A2 (0.49) THRATHRBPPARGPPARDPPARA
SCHEMBL7734076 0.88 CYP1A2 (0.48) THRATHRBPPARGPPARDPPARA
SCHEMBL7737487 0.87 HPGD (0.48) THRATHRBKDM4EALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN claimed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US claimed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN claimed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP claimed
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed