Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114074 | 0.94 | KMT2A (0.58) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL4226890 | 0.92 | KMT2A (0.53) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL3032065 | 0.88 | KMT2A (0.49) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL973673 | 0.84 | KMT2A (0.69) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL12265856 | 0.81 | KMT2A (0.51) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL8532867 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL3030211 | 0.80 | KMT2A (0.58) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL29114079 | 0.80 | MAPT (0.53) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL3022185 | 0.79 | L3MBTL1 (0.45) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL1747970 | 0.78 | KMT2A (0.59) | KMT2AMEN1NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792271-B1 | FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM | UNIV GEORGIA STATE RES FOUND (US) | 2002-02-27 | — | — | EP | disclosed |
| US-5602172-A | USING A 2,5-DIPHENYLFURAN COMPOUND | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-02-11 | — | — | US | disclosed |