Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.52 |
| ▸ | CTSS | P25774 | 9/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 7/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467412 | 1.00 | CTSL (0.52) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL13201878 | 0.89 | CTSS (0.57) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL15271340 | 0.89 | CTSS (0.57) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL9633851 | 0.87 | TACR1 (0.60) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL6348416 | 0.87 | TACR1 (0.60) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL9633248 | 0.87 | TACR1 (0.60) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL6552558 | 0.87 | TACR1 (0.60) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL8006799 | 0.86 | CTSS (0.64) | CTSLCTSSTACR1CTSBCTSK | |
| SCHEMBL10477767 | 0.84 | CTSK (0.62) | CTSLCTSSCTSBCTSK | |
| SCHEMBL30484700 | 0.83 | CTSS (0.50) | CTSLCTSSTACR1CTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |