Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694509 | 0.82 | CYP1A2 (0.51) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL9128626 | 0.81 | ALDH1A1 (0.55) | CYP1A2EGFRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7117086 | 0.81 | CYP4F2 (0.49) | CYP1A2ALDH1A1MAPT | |
| SCHEMBL7724935 | 0.80 | MEN1 (0.49) | KDM4ELTB4RMEN1ALDH1A1MAPT | |
| SCHEMBL2541520 | 0.79 | PTGER4 (0.61) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL17274556 | 0.78 | MTNR1A (0.45) | KDM4ECYP1A2EGFRMEN1ALDH1A1 | |
| SCHEMBL2536319 | 0.78 | CYP4F2 (0.55) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL1024737 | 0.77 | CYP1A2 (0.55) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL7725121 | 0.77 | BACE1 (0.55) | HDAC1BACE1 | |
| SCHEMBL9362082 | 0.77 | PTGER1 (0.48) | LTB4RALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |