Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735329 | 0.89 | LTB4R (0.51) | ALDH1A1PPARGPPARAPPARDLTB4R | |
| SCHEMBL28915626 | 0.83 | PPARD (0.64) | MEN1ALDH1A1KMT2AMAPTPPARG | |
| SCHEMBL7737515 | 0.80 | THRA (0.49) | ALDH1A1MAPTKDM4EPPARGPPARA | |
| SCHEMBL7734087 | 0.80 | HDAC1 (0.52) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL25168679 | 0.79 | PPARG (0.62) | MEN1ALDH1A1KMT2AMAPTPPARG | |
| SCHEMBL27406195 | 0.79 | PPARG (0.53) | PPARGPPARAPPARDLTB4RPTPN11 | |
| Biphenyl SCHEMBL27531294 | 0.77 | KDM4E (0.53) | MEN1ALDH1A1KMT2AKDM4EPPARG | |
| SCHEMBL7737650 | 0.77 | THRA (0.53) | ALDH1A1KDM4EPPARGPPARALTB4R | |
| SCHEMBL7725111 | 0.76 | PTPN1 (0.56) | ALDH1A1KDM4EPPARGPPARASLC6A9 | |
| Biphenyl SCHEMBL27297957 | 0.76 | POLB (0.55) | MEN1KMT2AKDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |