Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723473 | 0.91 | ALDH1A1 (0.38) | ALDH1A1HDAC3HDAC1HDAC2CNR2 | |
| SCHEMBL7734092 | 0.83 | MAPT (0.40) | ALDH1A1HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL7731622 | 0.83 | KCNH2 (0.34) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL7723476 | 0.82 | CYP2C9 (0.48) | ALDH1A1HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL7734089 | 0.79 | PDE4B (0.41) | ALDH1A1CNR2PDE4BPDE4DKMT2A | |
| SCHEMBL7723471 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PDE4BPDE4DKMT2AMEN1 | |
| SCHEMBL10948919 | 0.76 | MGLL (0.45) | ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8945263 | 0.75 | CYP2C9 (0.52) | ALDH1A1HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL7731623 | 0.75 | SLC18A3 (0.36) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL27841287 | 0.71 | CHRM1 (0.46) | ALDH1A1CNR2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |