Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734089 | 0.87 | PDE4B (0.41) | MAPTALDH1A1HCAR3LMNAKMT2A | |
| SCHEMBL7723476 | 0.86 | CYP2C9 (0.48) | MAPTALDH1A1TDP1HDAC3HDAC1 | |
| SCHEMBL7731623 | 0.84 | SLC18A3 (0.36) | MAPTALDH1A1SLC18A3LMNAKMT2A | |
| SCHEMBL7723473 | 0.83 | ALDH1A1 (0.38) | MAPTALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL7734090 | 0.83 | ALDH1A1 (0.36) | MAPTALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8945263 | 0.79 | CYP2C9 (0.52) | MAPTALDH1A1TDP1SLC18A3HDAC3 | |
| SCHEMBL27430080 | 0.77 | VCAM1 (0.56) | MAPTALDH1A1SLC18A3HCAR3LMNA | |
| SCHEMBL27784038 | 0.76 | GAA (0.47) | MAPTALDH1A1HCAR3KMT2AGAA | |
| SCHEMBL7723471 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7731618 | 0.74 | ACHE (0.35) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |