Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23532430 | 0.82 | TSHR (0.52) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL31643991 | 0.82 | TSHR (0.44) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL23040262 | 0.80 | NR1H3 (0.47) | TSHRMAPK1 | |
| SCHEMBL13731058 | 0.80 | TSHR (0.50) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL15736905 | 0.78 | CES2 (0.48) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL12879422 | 0.78 | ACHE (0.50) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL11418076 | 0.78 | CES2 (0.48) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL18238963 | 0.77 | NR1H2 (0.47) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL3153761 | 0.77 | TSHR (0.47) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL18234136 | 0.77 | TSHR (0.47) | TSHRMAPK1CES2MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399733-B1 | SILICONES | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2002-06-04 | — | — | US | disclosed |