Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 3/20 | 0.38 |
| ▸ | KLK14 | Q9P0G3 | 3/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724833 | 0.85 | PGK1 (0.45) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL2490307 | 0.82 | ELANE (0.41) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL7735271 | 0.82 | MAOB (0.41) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL7733881 | 0.79 | NLRP3 (0.36) | MAPTC1RHTTKDM4EALDH1A1 | |
| SCHEMBL7734319 | 0.78 | AKR1B1 (0.34) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL7737446 | 0.77 | PGK1 (0.35) | MEN1KMT2AALDH1A1PGK1 | |
| SCHEMBL7737473 | 0.77 | MEN1 (0.39) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL7724920 | 0.76 | NPC1 (0.42) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL7733971 | 0.75 | MAPT (0.46) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL7735657 | 0.75 | NPC1 (0.49) | NPC1RAB9ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |