Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724872 | 0.92 | GAA (0.36) | PGK1ALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL7733881 | 0.87 | NLRP3 (0.36) | PGK1AKR1B1ALDH1A1 | |
| SCHEMBL7735654 | 0.86 | NPC1 (0.42) | MEN1KMT2A | |
| SCHEMBL7737473 | 0.86 | MEN1 (0.39) | AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL7737540 | 0.84 | MAPT (0.44) | PGK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7724886 | 0.84 | SMN1; SMN2 (0.35) | PGK1AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL7734791 | 0.82 | RAB9A (0.39) | AKR1B1ALDH1A1KMT2A | |
| SCHEMBL7734319 | 0.81 | AKR1B1 (0.34) | PGK1AKR1B1ALDH1A1TAAR1MEN1 | |
| SCHEMBL7735204 | 0.78 | PGK1 (0.38) | PGK1AKR1B1ALDH1A1 | |
| SCHEMBL7734760 | 0.77 | MAPT (0.42) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |