Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434064 | 0.89 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28252448 | 0.89 | CA12 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28925286 | 0.89 | CA12 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4830387 | 0.89 | ALDH1A1 (0.53) | CA1CA2CA9CA12CA7 | |
| SCHEMBL8156698 | 0.89 | NR4A2 (0.49) | CA1CA2CA9CA12CA7 | |
| SCHEMBL403705 | 0.87 | CA12 (0.64) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1666445 | 0.87 | CA1 (0.64) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11101842 | 0.87 | NR4A2 (0.47) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28421849 | 0.86 | CA12 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27754773 | 0.86 | CA12 (0.46) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10449168-B2 | Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors | THE UNIVERSITY OF TOLEDO (US) | 2019-10-22 | — | — | US | claimed |
| US-20180250252-A1 | POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS | THE UNIVERSITY OF TOLEDO (US) | 2018-09-06 | — | — | US | claimed |
| CN-105622800-B | A kind of catalytic component and its catalyst system for olefinic polyreaction | 中国石油化工股份有限公司 | 2017-12-19 | — | — | CN | claimed |
| WO-2017040376-A1 | POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS | THE UNIVERSITY OF TOLEDO (US) | 2017-03-09 | — | — | WO | claimed |
| CN-103524304-B | Preparation method of 1,4-cyclohexanedimethanol | SHANGYU SUNFIT CHEMICAL CO LTD | 2015-02-04 | — | — | CN | claimed |
| CN-102559032-B | Low-temperature spraying combination material, and preparation method and application of low-temperature spraying combination material | SHANGHAI FUJIA FINE CHEMICAL CO LTD | 2014-05-07 | — | — | CN | claimed |
| JP-58005379-A | — | — | None | — | — | JP | disclosed |
| WO-2023249968-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIDO[2,3-DJPYRIMIDIN-7(8H)-ONE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| CN-112692725-B | Composition for polishing pad and polishing pad | SKC索密思株式会社 | 2023-05-16 | — | — | CN | disclosed |
| EP-4051674-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2022-09-07 | — | — | EP | disclosed |
| WO-2022140472-A1 | COMPOUNDS FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEOSOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2021131980-A1 | BINDER COMPOSITION FOR NON-AQUEOUS SECONDARY BATTERY ELECTRODES, SLURRY COMPOSITION FOR NON-AQUEOUS SECONDARY BATTERY ELECTRODES, ELECTRODE FOR NON-AQUEOUS SECONDARY BATTERIES, AND NON-AQUEOUS SECONDARY BATTERY | 日本ゼオン株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021083949-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2021-05-06 | — | — | WO | disclosed |
| US-20070161648-A1 | Substituted dihydro-isoindolones useful in treating kinase disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-07-12 | — | — | US | disclosed |
| WO-2007047646-A2 | SUBSTITUTED DIHYDRO-ISOINDOLONES USEFUL IN TREATING KINASE DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007047646-A2 | SUBSTITUTED DIHYDRO-ISOINDOLONES USEFUL IN TREATING KINASE DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007027527-A2 | ISOINDOLE-IMIDE COMPOUNDS AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORPORATION (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-1999050259-A2 | SYNTHESIS OF POLYSUBSTITUTED AROMATIC COMPOUNDS AND AROMATISATION PROCESS FOR USE THEREIN | WHITE KNIGHT BIOTECHNOLOGIES LIMITED (GB) | 1999-10-07 | — | — | WO | disclosed |
| JP-S585379-A | SOLVENT TYPE PAINT | SHIRAISHI CHUO KENKYUSHO:KK | 1983-01-12 | — | — | JP | disclosed |
| US-4303695-A | ACTINIC RADIATION CURABLE COATING | BISCAYNE DECORATIVE PRODUCTS, INC. (US) | 1981-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10449168-B2 | Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors | NAT1, SAT1, NAALAD2 | CA1 451/4885CA2 1090/4885CA9 836/4885 |
| US-20180250252-A1 | POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS | NAT1, SAT1, NAALAD2 | CA1 451/4885CA2 1090/4885CA9 836/4885 |
| US-20070161648-A1 | Substituted dihydro-isoindolones useful in treating kinase disorders | MAP3K20, MAP3K3, MAP3K19 | CA1 4754/4885CA2 3849/4885CA9 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.