⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370793 | 0.69 | — | — | |
| SCHEMBL21488269 | 0.69 | — | — | |
| SCHEMBL3107747 | 0.68 | — | — | |
| SCHEMBL18051624 | 0.67 | TSHR (0.45) | — | |
| SCHEMBL943478 | 0.67 | — | — | |
| SCHEMBL941560 | 0.67 | — | — | |
| SCHEMBL76665 | 0.67 | — | — | |
| SCHEMBL77233 | 0.66 | NUDT1 (0.30) | — | |
| SCHEMBL8624791 | 0.66 | — | — | |
| SCHEMBL1856794 | 0.66 | NUDT1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407211-B1 | Dendroaspis(green mamba snake) natriuretic peptide has at least one activity selected from the group consisting of vasodilation, antriuresis, diuresis and renin-suppressing activity | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2002-06-18 | — | — | US | disclosed |
| EP-0710491-A1 | Subdermally implantable device | THE POPULATION COUNCIL, CENTER FOR BIOMEDICAL RESEARCH (US) | 1996-05-08 | — | — | EP | disclosed |