SCHEMBL7734727

SCHEMBL7734727

COc1ccc(-c2ccccc2)cc1CCCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.47
FFAR4 Q5NUL3 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
CAPN1 P07384 2/20 0.47
PDE4A P27815 2/20 0.46
PDE4B Q07343 2/20 0.46
PDE4C Q08493 2/20 0.46
PDE4D Q08499 2/20 0.46
HTT P42858 1/20 0.46
PTGER1 P34995 2/20 0.45
PTGER4 P35408 2/20 0.45
PTGER3 P43115 2/20 0.45
PTGER2 P43116 2/20 0.45
NR1H4 Q96RI1 1/20 0.45
LTB4R Q15722 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735329 0.84 LTB4R (0.51) FFAR1FFAR4ALDH1A1PTGER1PTGER4
SCHEMBL10836143 0.83 PTGER4 (0.55) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL10836127 0.82 HDAC3 (0.54) FFAR1HPGD
SCHEMBL3264881 0.82 HPGD (0.57) HPGDLMNA
SCHEMBL10836064 0.81 SLC13A5 (0.59) FFAR1FFAR4ALDH1A1PTGER1PTGER4
SCHEMBL11433418 0.81 HSD17B10 (0.67) CAPN1
SCHEMBL8996459 0.81 FFAR4 (0.56) FFAR1FFAR4ALDH1A1HPGDLMNA
SCHEMBL7412627 0.79 FFAR4 (0.50) FFAR1FFAR4MAPTLMNA
SCHEMBL10836137 0.79 MTNR1A (0.56) HPGDLTB4RLMNA
SCHEMBL5036095 0.79 NR1H4 (0.52) HTTNR1H4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed