SCHEMBL7735329

SCHEMBL7735329

CCCCOc1ccc(-c2ccccc2)cc1CCCC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 5/20 0.51
LTB4R2 Q9NPC1 3/20 0.50
FFAR4 Q5NUL3 3/20 0.50
FFAR1 O14842 2/20 0.50
SLC6A9 P48067 2/20 0.49
PTPN11 Q06124 4/20 0.47
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ACLY P53396 1/20 0.46
PTGER1 P34995 1/20 0.46
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46
PPARG P37231 2/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724935 0.89 MEN1 (0.49) LTB4RSLC6A9PTPN11ALDH1A1PPARG
SCHEMBL30929658 0.85 PTPN11 (0.67) LTB4RPTPN11PTPN1PTPN6ALDH1A1
SCHEMBL27245958 0.85 PTPN11 (0.67) LTB4RPTPN11PTPN1PTPN6ALDH1A1
SCHEMBL27245970 0.84 PTPN11 (0.68) LTB4RLTB4R2PTPN11PTPN1PTPN6
SCHEMBL7734727 0.84 FFAR1 (0.47) LTB4RFFAR4FFAR1ALDH1A1PTGER1
SCHEMBL27406195 0.81 PPARG (0.53) LTB4RSLC6A9PTPN11PPARGPPARD
SCHEMBL7734091 0.79 PPARG (0.47) SLC6A9PTPN11PTPN1PTPN6PPARG
SCHEMBL7724925 0.79 THRA (0.52) FFAR4FFAR1SLC6A9ALDH1A1PTGER1
SCHEMBL27288709 0.77 PTPN11 (0.74) SLC6A9PTPN11PTPN1PTPN6
SCHEMBL27406194 0.77 CYSLTR2 (0.46) FFAR4FFAR1SLC6A9PTPN11PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed