SCHEMBL7734833

SCHEMBL7734833

CCCCCc1ccc(C(F)(F)Oc2ccc(CCc3ccc(OC(F)(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.39
S1PR3 Q99500 1/20 0.39
HTR2A P28223 1/20 0.35
FAAH O00519 1/20 0.35
SLC7A5 Q01650 1/20 0.35
PSEN1 P49768 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735298 0.96 S1PR1 (0.42) S1PR1S1PR3SLC7A5PSEN1PPARG
SCHEMBL7735441 0.94 SLC7A5 (0.38) S1PR1S1PR3HTR2AFAAHSLC7A5
SCHEMBL7730619 0.93 SLC7A5 (0.38) S1PR1S1PR3HTR2AFAAHSLC7A5
SCHEMBL7731909 0.92 DAO (0.36) S1PR1S1PR3SLC7A5PPARA
SCHEMBL7731908 0.91 RARB (0.46) S1PR1S1PR3PPARA
SCHEMBL7733382 0.91 SLC7A5 (0.38) S1PR1S1PR3FAAHSLC7A5PSEN1
SCHEMBL7729314 0.89 SLC7A5 (0.39) S1PR1S1PR3FAAHSLC7A5PSEN1
SCHEMBL7722896 0.89 DAO (0.39) SLC7A5PPARA
SCHEMBL7733331 0.88 S1PR1 (0.38) S1PR1S1PR3HTR2AFAAHPSEN1
SCHEMBL7730600 0.87 RARB (0.41) S1PR1S1PR3SLC7A5PSEN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed