SCHEMBL7734877

SCHEMBL7734877

C=CCOc1ccc(-c2cc(CCC(=O)OC)ccc2OCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.50
C5AR1 P21730 2/20 0.46
FFAR4 Q5NUL3 5/20 0.46
PTPN1 P18031 2/20 0.45
FFAR1 O14842 10/20 0.44
APP P05067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887117 0.83 CCNC (0.52) C5AR1FFAR4PTPN1FFAR1APP
SCHEMBL7725329 0.82 GAA (0.43) PTPN1FFAR1
SCHEMBL4895293 0.78 FFAR4 (0.52) FFAR4PTPN1FFAR1APP
SCHEMBL11023299 0.78 ADRB2 (0.53) FFAR1
SCHEMBL3881998 0.77 ENPP2 (0.53) C5AR1FFAR4PTPN1FFAR1APP
SCHEMBL1747445 0.76 FFAR1 (0.71) FFAR4FFAR1
SCHEMBL3882028 0.76 CCNC (0.49) FFAR4PTPN1FFAR1
SCHEMBL22982794 0.76 KDM4E (0.52) BCHE
SCHEMBL3625937 0.76 MAPT (0.49) C5AR1FFAR4FFAR1
SCHEMBL7725111 0.76 PTPN1 (0.56) C5AR1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed