Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023299 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1MEN1KMT2AFFAR1 | |
| SCHEMBL29100417 | 0.83 | ALOX5 (0.55) | GAAMGAMSIMGAM2ALOX5 | |
| SCHEMBL7734877 | 0.82 | BCHE (0.50) | PTPN1FFAR1 | |
| SCHEMBL7734908 | 0.81 | PTPN1 (0.48) | GAAALOX5GABRA1GABRB2CNR2 | |
| SCHEMBL10704484 | 0.79 | PTPN1 (0.46) | ALOX5GABRA1GABRB2PTPN1MEN1 | |
| SCHEMBL7737580 | 0.79 | PTPN1 (0.60) | GAAALOX5GABRA1GABRB2CNR2 | |
| SCHEMBL22982794 | 0.77 | KDM4E (0.52) | GAAADRB2ADRB1PPARD | |
| SCHEMBL12646491 | 0.77 | VDR (0.47) | GAAFFAR1VDRPPARDRXRA | |
| SCHEMBL3685390 | 0.76 | CCNC (0.58) | ALOX5GABRA1GABRB2PTPN1BACE1 | |
| SCHEMBL11281192 | 0.74 | ADRB2 (0.49) | ADRB2ADRB1MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |