Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735477 | 0.89 | ALDH1A1 (0.50) | THRATHRBALDH1A1KMT2AMEN1 | |
| SCHEMBL7724906 | 0.86 | THRA (0.61) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL3883525 | 0.83 | THRA (0.48) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL7734115 | 0.83 | THRA (0.54) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL7735322 | 0.82 | THRA (0.55) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL7734914 | 0.82 | THRA (0.55) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL1013811 | 0.81 | THRA (0.54) | THRATHRBFFAR1KMT2AMEN1 | |
| SCHEMBL7725082 | 0.81 | THRA (0.53) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL7725137 | 0.81 | THRA (0.52) | THRATHRBFFAR1ALDH1A1KMT2A | |
| SCHEMBL7737493 | 0.80 | THRB (0.48) | THRATHRBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | claimed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | claimed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |