Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13814815 | 0.93 | MAPK1 (0.84) | MAPK1POLBLMNAL3MBTL1CA1 | |
| SCHEMBL1938690 | 0.93 | MAPK1 (0.84) | MAPK1POLBLMNAL3MBTL1CA1 | |
| SCHEMBL7740826 | 0.91 | MAPK1 (0.60) | MAPK1POLBLMNAL3MBTL1CA1 | |
| SCHEMBL9717451 | 0.91 | MAPK1 (0.85) | MAPK1POLBLMNACA1CA2 | |
| SCHEMBL279993 | 0.89 | LMNA (0.71) | MAPK1POLBLMNAL3MBTL1CA1 | |
| SCHEMBL19133523 | 0.86 | LMNA (0.71) | MAPK1POLBLMNAL3MBTL1NPC1 | |
| SCHEMBL9489979 | 0.85 | L3MBTL1 (0.86) | MAPK1POLBLMNAL3MBTL1NPC1 | |
| SCHEMBL23794423 | 0.84 | MAPK1 (0.74) | MAPK1POLBLMNACA1CA2 | |
| SCHEMBL2033165 | 0.84 | MAPK1 (0.73) | MAPK1LMNACA1CA2NPC1 | |
| SCHEMBL428355 | 0.84 | MAPK1 (1.00) | MAPK1POLBLMNAL3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | claimed |
| US-20220007684-A1 | APPLICATION OF ACYLATED DERIVATIVE OF AMINO ACID IN PREPARATION OF ANIMAL FEED ADDITIVE | Anipha Technologies Pty Ltd (AU) | 2022-01-13 | — | — | US | disclosed |
| US-20220007684-A1 | APPLICATION OF ACYLATED DERIVATIVE OF AMINO ACID IN PREPARATION OF ANIMAL FEED ADDITIVE | Anipha Technologies Pty Ltd (AU) | 2022-01-13 | — | — | US | disclosed |
| EP-3878287-A1 | APPLICATION OF ACYLATED DERIVATIVE OF AMINO ACID IN PREPARATION OF ANIMAL FEED ADDITIVE | Peng, Xianfeng (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3878287-A1 | APPLICATION OF ACYLATED DERIVATIVE OF AMINO ACID IN PREPARATION OF ANIMAL FEED ADDITIVE | Peng, Xianfeng (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-111629602-A | Application of acylated derivative of amino acid in preparation of animal feed additive | 黄华成 | 2020-09-04 | — | — | CN | disclosed |
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |