SCHEMBL7735154

SCHEMBL7735154

NC(=O)CCCOc1ccc(CCCC(N)=O)cc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 2/20 0.50
LMNA P02545 1/20 0.50
PTGDR2 Q9Y5Y4 5/20 0.47
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
SLC6A9 P48067 1/20 0.44
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
PDE4A P27815 2/20 0.44
PDE4B Q07343 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
PLAAT3 P53816 1/20 0.42
PLAAT5 Q96KN8 1/20 0.42
PLAAT2 Q9NWW9 1/20 0.42
PLAAT4 Q9UL19 1/20 0.42
LTB4R Q15722 1/20 0.41
BACE1 P56817 1/20 0.41
CYP1A2 P05177 1/20 0.41
CD274 Q9NZQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7737444 0.92 THRA (0.51) C5AR1LMNAPTGDR2PLA2G10PLA2G2A
SCHEMBL7734080 0.91 PTGDR2 (0.52) C5AR1PTGDR2PLA2G10PLA2G2APLAAT3
SCHEMBL7725029 0.90 CYP1A2 (0.52) PTGDR2PLA2G10PLA2G2ASLC6A9CYP1A2
SCHEMBL7724415 0.86 CYP1A2 (0.51) LMNAPTGDR2PLA2G10PLA2G2ASLC6A9
SCHEMBL7734112 0.86 PTGDR2 (0.53) PTGDR2PLA2G10PLA2G2ACYP1A2
SCHEMBL7735866 0.84 CYP1A2 (0.49) PTGDR2PLA2G10PLA2G2ASLC6A9THRA
SCHEMBL7734076 0.83 CYP1A2 (0.48) PTGDR2PLA2G10PLA2G2ASLC6A9THRA
SCHEMBL7724925 0.83 THRA (0.52) PTGDR2PLA2G10PLA2G2ASLC6A9THRA
SCHEMBL7733989 0.82 THRA (0.56) PTGDR2PLA2G10PLA2G2ASLC6A9THRA
SCHEMBL7735325 0.82 CYP1A2 (0.47) PTGDR2PLA2G10PLA2G2ASLC6A9THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US claimed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP claimed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed