SCHEMBL7735156

SCHEMBL7735156

CCN(CC)CCn1c(=O)c(-c2ccccc2)c(O)c2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.74
GAA P10253 2/20 0.74
RCE1 Q9Y256 1/20 0.71
ALDH1A1 P00352 3/20 0.70
MAPT P10636 2/20 0.67
KMT2A Q03164 3/20 0.60
LMNA P02545 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
TOP2A P11388 1/20 0.56
HIF1A Q16665 1/20 0.55
G6PD P11413 1/20 0.55
SLC6A4 P31645 2/20 0.49
HPGD P15428 2/20 0.49
POLB P06746 2/20 0.49
HSD17B10 Q99714 1/20 0.49
SLC6A2 P23975 1/20 0.49
HRH1 P35367 1/20 0.49
EGFR P00533 1/20 0.48
RECQL P46063 1/20 0.48
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703956 0.76 SLC6A4 (0.78) KDM4EGAAALDH1A1MAPTSMN1; SMN2
SCHEMBL11736890 0.76 G6PD (0.63) GAAMAPTKMT2ALMNASMN1; SMN2
SCHEMBL2334457 0.75 POLB (0.63) KDM4EGAARCE1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL11730203 0.75 G6PD (0.62) GAAMAPTKMT2ALMNASMN1; SMN2
SCHEMBL11559119 0.73 ALDH1A1 (0.56) KDM4EGAAALDH1A1MAPTKMT2A
SCHEMBL1966502 0.72 PKM (0.64) KDM4EGAAALDH1A1KMT2ATOP2A
SCHEMBL8337087 0.72 KDM4E (0.62) KDM4EGAARCE1ALDH1A1MAPT
SCHEMBL11732985 0.71 G6PD (0.60) KDM4EGAAALDH1A1MAPTKMT2A
SCHEMBL6498221 0.71 KMT2A (0.55) KDM4EALDH1A1KMT2ASMN1; SMN2TOP2A
SCHEMBL13418980 0.70 HIF1A (0.56) KDM4EGAAMAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410536-B1 ANTICOAGULANTS WARNER-LAMBERT COMPANY 2002-06-25 US disclosed