Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884514 | 0.90 | CCNC (0.43) | THRATHRBPTPN1CYP19A1ALDH1A1 | |
| SCHEMBL7737493 | 0.85 | THRB (0.48) | THRATHRBPTPN1C5AR1ALDH1A1 | |
| SCHEMBL7725159 | 0.85 | THRA (0.47) | THRATHRBPTPN1C5AR1ALDH1A1 | |
| SCHEMBL3882371 | 0.84 | THRA (0.36) | THRATHRBCYP19A1ALDH1A1 | |
| SCHEMBL3884481 | 0.83 | CHRNA7 (0.37) | THRATHRB | |
| SCHEMBL7725103 | 0.83 | THRA (0.44) | THRATHRBPTPN1C5AR1CYP19A1 | |
| SCHEMBL3688206 | 0.82 | THRA (0.57) | THRATHRBCYP19A1ALDH1A1MEN1 | |
| SCHEMBL7735292 | 0.82 | C5AR1 (0.47) | THRATHRBPTPN1C5AR1ALDH1A1 | |
| SCHEMBL7733919 | 0.82 | THRA (0.45) | THRATHRBPTPN1C5AR1ALDH1A1 | |
| SCHEMBL7737488 | 0.82 | PTPN1 (0.44) | THRATHRBPTPN1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |