Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735710 | 0.95 | ALDH1A1 (0.45) | PTPN1ALDH1A1MAPTTDP1AKR1C3 | |
| SCHEMBL7734876 | 0.91 | THRA (0.47) | ALDH1A1MAPTTDP1AKR1C3AKR1C2 | |
| SCHEMBL7734073 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPTTDP1AKR1C3AKR1C2 | |
| SCHEMBL27627101 | 0.88 | CCNC (0.46) | PTPN1ALDH1A1TDP1LMNACNR2 | |
| SCHEMBL3893514 | 0.84 | CCNC (0.46) | PTPN1ALDH1A1MAPT | |
| SCHEMBL7737564 | 0.83 | PTPN1 (0.45) | PTPN1AKR1C3KMT2AMEN1CNR2 | |
| SCHEMBL27406924 | 0.83 | LTB4R (0.41) | ALDH1A1MAPTTDP1AKR1C3AKR1C2 | |
| SCHEMBL27627098 | 0.82 | CCNC (0.46) | PTPN1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL7735167 | 0.82 | THRA (0.44) | PTPN1ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL7735380 | 0.81 | PTPN1 (0.44) | PTPN1ALDH1A1AKR1C3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |