Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734849 | 0.89 | PTGDR2 (0.53) | PTGDR2TP53MDM2FFAR4 | |
| SCHEMBL7735802 | 0.87 | PTPN1 (0.54) | PTPN1PTGDR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7735881 | 0.87 | PTPN1 (0.56) | PTPN1PTGDR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7725111 | 0.85 | PTPN1 (0.56) | PTPN1PTGDR2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7734899 | 0.84 | PTPN1 (0.55) | PTPN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27403097 | 0.82 | PTPN1 (0.56) | PTPN1PTGDR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7735868 | 0.82 | PTPN1 (0.58) | PTPN1PTGDR2KMT2ASIRT2TP53 | |
| SCHEMBL7735390 | 0.82 | PTPN1 (0.55) | PTPN1LMNATSHRSMN1; SMN2TP53 | |
| SCHEMBL7734915 | 0.81 | PTPN1 (0.48) | PTPN1PTGDR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7725041 | 0.80 | ALDH1A1 (0.48) | PTPN1PTGDR2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |