SCHEMBL7734849

SCHEMBL7734849

CCC(=O)COc1ccc(CCC(=O)O)cc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 9/20 0.53
FFAR4 Q5NUL3 5/20 0.50
FFAR1 O14842 6/20 0.49
TP53 P04637 2/20 0.48
MDM2 Q00987 2/20 0.48
BCL2L1 Q07817 1/20 0.48
MCL1 Q07820 1/20 0.48
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735347 0.89 PTPN1 (0.55) PTGDR2FFAR4TP53MDM2
SCHEMBL7735506 0.88 PTGDR2 (0.63) PTGDR2FFAR4FFAR1TP53MDM2
SCHEMBL7724946 0.85 PTGDR2 (0.56) PTGDR2FFAR4FFAR1TP53MDM2
SCHEMBL7734788 0.84 RXRA (0.53) FFAR4FFAR1PPARGPPARDPPARA
SCHEMBL7734086 0.82 THRA (0.57) PTGDR2FFAR4FFAR1PPARGPPARD
SCHEMBL7725124 0.81 FFAR1 (0.58) FFAR4FFAR1TP53MDM2
SCHEMBL7734883 0.81 TP53 (0.52) PTGDR2FFAR4FFAR1TP53MDM2
SCHEMBL7725122 0.81 PTGDR2 (0.60) PTGDR2FFAR1TP53MDM2BCL2L1
SCHEMBL7735382 0.81 FFAR4 (0.48) PTGDR2FFAR4FFAR1TP53MDM2
SCHEMBL27404781 0.80 FFAR1 (0.51) PTGDR2FFAR4FFAR1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN claimed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US claimed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN claimed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP claimed
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed