SCHEMBL7735443

SCHEMBL7735443

Cc1ccc(C)c(S)c1.[LiH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP2A6 P11509 4/20 0.41
CYP1A2 P05177 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
TP53 P04637 2/20 0.40
TAAR1 Q96RJ0 1/20 0.38
ACHE P22303 3/20 0.37
HSD17B10 Q99714 2/20 0.37
GAA P10253 2/20 0.37
RAPGEF4 Q8WZA2 1/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438518 0.97
SCHEMBL394229 0.97
SCHEMBL9231006 0.85 ALDH1A1 (0.39) TDP1ALDH1A1CYP2A6CYP1A2SMN1; SMN2
SCHEMBL7054879 0.80 ALDH1A1 (0.35) TDP1ALDH1A1CYP2A6CYP1A2SMN1; SMN2
SCHEMBL7741500 0.78 TDP1 (0.46) TDP1ALDH1A1CYP2A6CYP1A2SMN1; SMN2
SCHEMBL331198 0.77
SCHEMBL29373274 0.77
SCHEMBL234687 0.74
SCHEMBL63648 0.74
SCHEMBL29511362 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413677-B1 THIOCARBONATE ELECTROLYTE UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed