SCHEMBL7735682

SCHEMBL7735682

CCO[PH](=O)OC(C(=O)c1c(C)cc(C(C)(C)C)cc1C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
PPARG P37231 4/20 0.35
LMNA P02545 2/20 0.35
ALDH1A1 P00352 1/20 0.35
EPHX1 P07099 3/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TACR1 P25103 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MMP8 P22894 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183300 0.89 MEN1 (0.41) PPARACYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL7181525 0.87 L3MBTL1 (0.40) PPARACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL7187136 0.85 PPARA (0.37) PPARACYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL7177113 0.79 MAPT (0.37) PPARAPPARGLMNAALDH1A1GAA
SCHEMBL7183743 0.78 PPARA (0.38) PPARACYP3A4PPARGLMNAALDH1A1
SCHEMBL7187009 0.78 PPARG (0.35) PPARACYP1A2CYP3A4CYP2C9PPARG
SCHEMBL7181329 0.77 CA12 (0.42) PPARATSHRLMNAALDH1A1MEN1
SCHEMBL7181130 0.77 TDP1 (0.39) CYP3A4MEN1KMT2ATACR1
SCHEMBL7181116 0.73 MMP8 (0.50) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL7176038 0.73 ALDH1A1 (0.39) PPARALMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 PPARA 2624/4885CYP1A2 2020/4885CYP3A4 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.