Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259257 | 0.85 | HPGD (0.63) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL29931971 | 0.79 | HTT (0.59) | ATMPOLBSMN1; SMN2CYP2C19MAPT | |
| SCHEMBL308530 | 0.78 | L3MBTL1 (0.47) | L3MBTL1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL31053522 | 0.77 | TDP1 (0.38) | L3MBTL1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7313251 | 0.76 | KDM4E (0.77) | RAB9AKDM4EPOLBNPC1SMN1; SMN2 | |
| SCHEMBL4055295 | 0.76 | ALDH1A1 (0.43) | L3MBTL1SMN1; SMN2CYP2C19MAPTALDH1A1 | |
| SCHEMBL29932078 | 0.76 | KMT2A (0.46) | KDM4EPOLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30885149 | 0.76 | ACHE (0.47) | L3MBTL1RAB9ANPC1ALDH1A1KMT2A | |
| Diphenylamine SCHEMBL28610391 | 0.75 | MAPT (0.67) | L3MBTL1RAB9AKDM4EPOLBNPC1 | |
| SCHEMBL7312797 | 0.73 | CYP1A2 (0.67) | L3MBTL1KDM4ECYP2C19MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |
| US-6048900-A | FOR TREATING EATING DISORDERS, INSULIN RESISTANT DIABETES, HYPERTENSION, HYPERLIPEMIA | BAYER CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |