SCHEMBL7735807

SCHEMBL7735807

NC(=O)Nc1ccc2cccnc2n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
LMNA P02545 1/20 0.51
ALDH1A1 P00352 2/20 0.45
NR3C2 P08235 4/20 0.40
PARP1 P09874 2/20 0.40
GAA P10253 1/20 0.39
NPC1 O15118 4/20 0.37
RAB9A P51151 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27839553 0.85 KMT2A (0.57) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL11486599 0.83 KDM4E (0.51) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL1682467 0.83 CYP3A4 (0.51) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL1602180 0.77 ALDH1A1 (0.47) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL8138166 0.77 KDM4E (0.45) KDM4EKMT2AMEN1ALDH1A1NR3C2
SCHEMBL15530597 0.76 KMT2A (0.63) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL27556839 0.76 METAP1 (0.49) KDM4EKMT2AMEN1LMNAALDH1A1
Carbamic Acid SCHEMBL21437195 0.76 KDM4E (0.62) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL30576393 0.74 KDM4E (0.71) KDM4EKMT2AMEN1LMNAALDH1A1
SCHEMBL2360527 0.74 NPC1 (0.65) KMT2ANPC1RAB9AMAPTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118562128-A Modified polyimide binder, preparation method thereof, electrode plate and lithium ion battery 东莞东阳光科研发有限公司 2024-08-30 CN claimed
CN-118562128-A Modified polyimide binder, preparation method thereof, electrode plate and lithium ion battery 东莞东阳光科研发有限公司 2024-08-30 CN disclosed
US-6452008-B2 3-UREA COMPOUND FROM THE 3-AMIDO COMPOUND WITHOUT AZIDATION PROCESS WHICH HAS RISK OF EXPLOSION; REACTION WITH HYPOCHLORITE, HYPOBROMITE OR LEAD TETRAACETATE AND THEN AN AMINE; ACAT INHIBITOR SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20010051732-A1 Pyridone derivatives and process for preparing the same SUMITOMO PHARMACEUTICALS COMPANY, LIMITED 2001-12-13 US disclosed
US-6300500-B1 Preparation of pyridone derivatives using phthalimido containing starting material SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-10-09 US disclosed
EP-1086948-A1 PYRIDONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-03-28 EP disclosed
EP-1017694-A2 N-5,6,7,8-TETRAHYDRO(1,6)NAPHTHYRIDINE-N'-PHENYLUREA DERIVATIVES SMITHKLINE BEECHAM PLC (GB) 2000-07-12 EP disclosed
EP-0984967-A1 NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS BIOCHEM PHARMA INC (CA) 2000-03-15 EP disclosed
US-5945431-A VIRICIDE BIOCHEM THERAPEUTICS INCORPORATED (CA) 1999-08-31 US disclosed
WO-1999015526-A2 N-5,6,7,8-TETRAHYDRO(1,6)NAPHTHYRIDINE-N'-PHENYLUREA DERIVATIVES SMITHKLINE BEECHAM PLC (GB) 1999-04-01 WO disclosed
WO-1997034894-A1 NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS BIOCHEM PHARMA INC. (CA) 1997-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010051732-A1 Pyridone derivatives and process for preparing the same HK1, HPD, ALK KDM4E 139/4885KMT2A 578/4885MEN1 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.