Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970115 | 0.85 | KDM4E (0.46) | KDM4EHSP90AA1HSP90AB1NPC1KMT2A | |
| SCHEMBL27860315 | 0.83 | CYP3A4 (0.47) | KDM4EHSP90AA1HSP90AB1NPC1KMT2A | |
| SCHEMBL15690239 | 0.83 | KDM4E (0.66) | KDM4EHSP90AA1HSP90AB1NPC1KMT2A | |
| SCHEMBL8515227 | 0.79 | KDM4E (0.70) | KDM4EHSP90AA1HSP90AB1NPC1KMT2A | |
| SCHEMBL31054265 | 0.78 | KMT2A (0.68) | NPC1KMT2AMEN1POLBMAPT | |
| SCHEMBL2360527 | 0.77 | NPC1 (0.65) | NPC1KMT2AMAPTRAB9A | |
| SCHEMBL7735807 | 0.77 | KDM4E (0.51) | KDM4ENPC1KMT2AMEN1POLB | |
| Carbamic Acid SCHEMBL21437196 | 0.75 | ALDH1A1 (0.50) | KDM4ENPC1KMT2AMEN1POLB | |
| SCHEMBL15223280 | 0.74 | NCF1 (0.55) | KDM4EHSP90AA1HSP90AB1NPC1POLB | |
| SCHEMBL15726233 | 0.74 | JAK2 (0.53) | KDM4ENPC1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984967-A1 | NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS | BIOCHEM PHARMA INC (CA) | 2000-03-15 | — | — | EP | disclosed |
| US-5945431-A | VIRICIDE | BIOCHEM THERAPEUTICS INCORPORATED (CA) | 1999-08-31 | — | — | US | disclosed |
| WO-1997034894-A1 | NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS | BIOCHEM PHARMA INC. (CA) | 1997-09-25 | — | — | WO | disclosed |