Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12976274 | 0.93 | RARB (0.42) | RARBRARARARGMCL1CYP17A1 | |
| SCHEMBL13513492 | 0.91 | RARB (0.55) | RARBRARARARGHSD17B10THRB | |
| SCHEMBL2480683 | 0.87 | ERN1 (0.41) | RARBRARARARGCYP17A1CYP11B1 | |
| SCHEMBL7735973 | 0.86 | CNR1 (0.40) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL2883450 | 0.82 | RARB (0.44) | RARBRARARARGMCL1CYP17A1 | |
| SCHEMBL14449536 | 0.80 | ERN1 (0.44) | RARBRARARARGCYP17A1ERN1 | |
| SCHEMBL16258048 | 0.79 | CYP17A1 (0.53) | RARBRARARARGMCL1CYP17A1 | |
| SCHEMBL16258014 | 0.79 | CYP17A1 (0.53) | RARBRARARARGMCL1CYP17A1 | |
| SCHEMBL12976353 | 0.79 | RARB (0.40) | RARBRARARARGMCL1CYP17A1 | |
| SCHEMBL12976576 | 0.79 | RARB (0.40) | RARBRARARARGMCL1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372975-B2 | Liquid crystal compound having difluoropropenyleneoxy bonding group | JNC CORPORATION (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372975-B2 | Liquid crystal compound having difluoropropenyleneoxy bonding group | JNC CORPORATION (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8372975-B2 | Liquid crystal compound having difluoropropenyleneoxy bonding group | JNC CORPORATION (JP) | 2013-02-12 | — | — | US | disclosed |
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | CHISSO PETROCHEMICAL CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | CHISSO PETROCHEMICAL CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | CHISSO PETROCHEMICAL CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029194-A1 | LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP | LEF1, EIF4A3, TCF4 | RARB 3142/4885RARA 2088/4885RARG 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.