Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7736150 | 0.90 | CYP19A1 (0.44) | TOP1VCPPLAUCYP19A1CYP11B1 | |
| SCHEMBL6824271 | 0.82 | ADRA2A (0.44) | TOP1PLAUPLGPLATPDE4D | |
| Hydrochloric Acid SCHEMBL7727730 | 0.77 | ADRA2A (0.43) | TOP1PLAUPLGPLATCYP19A1 | |
| Hydrochloric Acid SCHEMBL7738341 | 0.76 | VCP (0.36) | VCPCYP19A1CYP11B1CYP11B2MEN1 | |
| SCHEMBL6734212 | 0.73 | MAPT (0.44) | TOP1RAB9ANPC1KEAP1NFE2L2 | |
| SCHEMBL1655585 | 0.72 | MAPT (0.56) | RAB9ANPC1PDE4DMEN1MAPT | |
| SCHEMBL8536108 | 0.68 | HTT (0.51) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL16148300 | 0.67 | NPC1 (0.48) | RAB9ANPC1MEN1MAPTKMT2A | |
| SCHEMBL16148298 | 0.67 | FGFR1 (0.51) | MAPTKMT2AHTT | |
| SCHEMBL8541523 | 0.66 | ADRA1A (0.54) | VCPCYP19A1PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410562-B1 | ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY | 2002-06-25 | — | — | US | disclosed |