SCHEMBL7736291

SCHEMBL7736291

O=C(O)c1ccccc1CCc1ccc(Oc2ccc(CCc3ccccc3C(=O)O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.56
FOLH1 Q04609 1/20 0.54
ALDH1A1 P00352 3/20 0.50
SRD5A2 P31213 2/20 0.50
TSHR P16473 1/20 0.50
ADRB2 P07550 1/20 0.50
MMP12 P39900 1/20 0.48
MMP13 P45452 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
LTA4H P09960 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5333596 0.87 USP2 (0.61) FFAR1FOLH1ALDH1A1FFAR4KMT2A
SCHEMBL166927 0.86 FOLH1 (0.66) FOLH1ALDH1A1TSHRADRB2LMNA
SCHEMBL29975597 0.86 FOLH1 (0.66) FOLH1ALDH1A1TSHRADRB2LMNA
SCHEMBL8702953 0.84 FOLH1 (0.63) FOLH1ALDH1A1TSHRADRB2LMNA
Hydrochloric Acid SCHEMBL7699238 0.84 FOLH1 (0.63) FOLH1ALDH1A1TSHRADRB2LMNA
SCHEMBL7764255 0.83 TSHR (0.72) FOLH1ALDH1A1TSHRADRB2LMNA
SCHEMBL70392 0.82 FOLH1 (0.76) FOLH1ALDH1A1TSHRADRB2HTT
SCHEMBL30365583 0.82 FOLH1 (0.76) FOLH1ALDH1A1TSHRADRB2HTT
SCHEMBL6387117 0.81 ALDH1A1 (0.67) FOLH1ALDH1A1TSHRADRB2LMNA
SCHEMBL5515624 0.81 FOLH1 (0.56) FOLH1ALDH1A1TSHRADRB2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002332346-A POLYMER, ITS PRODUCTION METHOD, AND COMPOSITION FOR FILM FORMATION CONTAINING THE SAME JSR CORP 2002-11-22 JP disclosed