Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737672 | 0.78 | PTGIR (0.44) | PTGIRSLC6A4 | |
| SCHEMBL7737194 | 0.72 | PTGIR (0.56) | PTGIRCYSLTR2CYSLTR1ALDH1A1KDM4E | |
| SCHEMBL7730002 | 0.69 | PTGIR (0.55) | PTGIRCYSLTR2CYSLTR1ALDH1A1TSHR | |
| SCHEMBL7730063 | 0.69 | PTGIR (0.55) | PTGIRCYSLTR2CYSLTR1ALDH1A1TSHR | |
| SCHEMBL7737347 | 0.69 | PTGIR (0.57) | PTGIRCYSLTR2CYSLTR1ALDH1A1KDM4E | |
| SCHEMBL7736474 | 0.68 | PPARD (0.44) | PTGIRALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL18783862 | 0.68 | PTGIR (0.41) | PTGIRCYSLTR2CYSLTR1ALDH1A1GAA | |
| SCHEMBL7736507 | 0.67 | PTGIR (0.63) | PTGIRCYSLTR2CYSLTR1ALDH1A1TSHR | |
| SCHEMBL7737053 | 0.67 | HTR1A (0.49) | PTGIRTSHRHTR1ASLC6A4MAPT | |
| SCHEMBL7739724 | 0.66 | PTGIR (0.54) | PTGIRCYSLTR2CYSLTR1TSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |