⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18446 | 0.82 | ALDH1A1 (0.53) | — | |
| SCHEMBL3133746 | 0.81 | ALDH1A1 (0.42) | — | |
| SCHEMBL2945943 | 0.78 | GAA (0.46) | — | |
| SCHEMBL2948744 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL23461700 | 0.76 | GAA (0.39) | — | |
| SCHEMBL16811766 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL125810 | 0.75 | — | — | |
| SCHEMBL27767863 | 0.75 | — | — | |
| SCHEMBL2941644 | 0.74 | — | — | |
| SCHEMBL2939615 | 0.74 | GAA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202372-B2 | Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2019-02-12 | — | — | US | disclosed |
| US-20150203489-A1 | TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF | UNIVERSITE D'ORLEANS (FR) | 2015-07-23 | — | — | US | disclosed |
| US-20020042018-A1 | Positive chemically amplified resist and method for forming its pattern | NEC CORPORATION | 2002-04-11 | — | — | US | disclosed |