Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16089554 | 0.79 | CA3 (0.39) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL25346822 | 0.79 | CA3 (0.39) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL13488 | 0.77 | CES2 (0.36) | CES2CES1 | |
| SCHEMBL12804172 | 0.75 | DAO (0.38) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL24978467 | 0.75 | TP53 (0.36) | KDM4EESR1ESR2 | |
| SCHEMBL24252843 | 0.75 | CYP3A4 (0.42) | KDM4EHSD17B1HSD17B2ESR2 | |
| SCHEMBL30467752 | 0.75 | CYP3A4 (0.42) | KDM4EHSD17B1HSD17B2ESR2 | |
| SCHEMBL155976 | 0.75 | CES2 (0.46) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL361051 | 0.73 | PIM1 (0.41) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL5506954 | 0.72 | ADRA2A (0.45) | CA3CA6CA5ACA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080132-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| CN-105980392-A | Bromodomain inhibitors | 艾伯维公司 | 2016-09-28 | — | — | CN | disclosed |
| WO-2015085925-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| US-6413448-B1 | ESTERS; DOPANTS; LONGER CHIRAL SMECTIC PHASE PITCH; HIGHER TILT ANGLE; LOWER VISCOSITY; CRYSTALLIZATION SUPPRESSION; IMPROVED SOLUBILITY; BROADER C* PHASE TEMPERATURE RANGE | DISPLAYTECH, INC. | 2002-07-02 | — | — | US | disclosed |
| WO-2000065801-A9 | CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE | DISPLAYTECH INC (US) | 2001-04-12 | — | — | WO | disclosed |
| WO-2000065801-A1 | CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE | DISPLAYTECH, INC. (US) | 2000-11-02 | — | — | WO | disclosed |