Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872339 | 0.83 | DUT (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28811139 | 0.82 | FABP7 (0.33) | LMNAMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28662854 | 0.75 | TP53 (0.34) | ALDH1A1MEN1KMT2ATDP1HTT | |
| SCHEMBL31374362 | 0.75 | MEN1 (0.32) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL10623743 | 0.71 | SLC7A5 (0.34) | KIF11IDO1 | |
| SCHEMBL29900 | 0.70 | LTA4H (0.37) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL31519130 | 0.70 | — | — | |
| SCHEMBL5596037 | 0.70 | SLC6A2 (0.37) | ALDH1A1MAPK1 | |
| SCHEMBL29033104 | 0.70 | — | — | |
| SCHEMBL10495731 | 0.68 | LTA4H (0.35) | TSHRALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652663-A | BONDING FLUOROSILICON RUBBERS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-03-24 | — | — | US | claimed |
| US-6414173-B1 | TRANSMETALLATION REACTION, COMPRISING: CONTACTING PALLADIUM CATALYST WITH AROYL, ALKANOYL, OR ARALKANOYL ESTER OF ALLYLIC ALCOHOL; AND HYPERVALENT SILICON SPECIES | UNIVERSITY OF MARYLAND | 2002-07-02 | — | — | US | disclosed |
| US-4652663-A | BONDING FLUOROSILICON RUBBERS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |