SCHEMBL31374362

SCHEMBL31374362

CO[Si](OC)(OCOCC(F)(F)F)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TACR1 P25103 1/20 0.31
FABP7 O15540 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1971501 0.81 POLB (0.32) ALDH1A1
SCHEMBL1969300 0.80
SCHEMBL1969396 0.78
SCHEMBL28811139 0.77 FABP7 (0.33) MEN1LMNAKMT2ATDP1L3MBTL1
SCHEMBL28351506 0.77 CA2 (0.35) MEN1LMNAKMT2AALDH1A1
SCHEMBL28307215 0.77 LMNA (0.33) MEN1LMNAKMT2AALDH1A1
SCHEMBL21294151 0.75 NCF1 (0.35) MEN1KMT2A
SCHEMBL28902645 0.75 ALDH1A1 (0.32) LMNAALDH1A1
SCHEMBL28928050 0.75 KIF11 (0.41)
SCHEMBL7737245 0.75 TSHR (0.37) MEN1LMNAKMT2ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192582-A Method for preparing vinyl fluorine-containing hyperbranched organic silicon resin with low viscosity 南京大学 2024-12-27 CN disclosed