Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737728 | 0.81 | HTR6 (0.45) | SLC5A2HTR6PKMDRD2HTR2A | |
| SCHEMBL7737292 | 0.77 | SLC5A2 (0.39) | SLC5A2HTR6PKMDRD2HTR2A | |
| SCHEMBL7737820 | 0.74 | PTGER3 (0.41) | SLC5A2HTR6PKMDRD2HTR2A | |
| SCHEMBL7737826 | 0.74 | PTGER3 (0.41) | SLC5A2HTR6PKMDRD2HTR2A | |
| SCHEMBL27499139 | 0.71 | CHRM1 (0.39) | SLC5A2HTR6DRD2HTR2AMCHR1 | |
| SCHEMBL19682942 | 0.68 | PKM (0.44) | SLC5A2HTR6PKMGAAALDH1A1 | |
| SCHEMBL7730166 | 0.67 | CHRM1 (0.38) | HTR6DRD2HTR2AMCHR1ALDH1A1 | |
| SCHEMBL14151328 | 0.64 | FFAR1 (0.35) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL7730214 | 0.63 | SLC6A4 (0.41) | DRD2HTR2AMCHR1 | |
| SCHEMBL2599677 | 0.63 | HTR6 (0.64) | HTR6ALDH1A1MEN1KMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202084-C | Fused benzene heterocycle derivatives and utilization thereof | TORAY INDUSTRIES (JP) | 2005-05-18 | — | — | CN | disclosed |
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| CN-1287553-A | Fused benzene heterocycle derivatives and utilization thereof | TORAY INDUSTRIES (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |