Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737826 | 0.83 | PTGER3 (0.41) | HTR6KMT2AMEN1GAACHRM1 | |
| SCHEMBL7737820 | 0.83 | PTGER3 (0.41) | HTR6KMT2AMEN1GAACHRM1 | |
| SCHEMBL7737673 | 0.81 | SLC5A2 (0.41) | HTR6KMT2AMEN1GAACHRM1 | |
| SCHEMBL27499139 | 0.80 | CHRM1 (0.39) | HTR6KMT2AMEN1GAACHRM1 | |
| SCHEMBL7729988 | 0.79 | HTR6 (0.41) | HTR6KMT2AMEN1GAACHRM1 | |
| SCHEMBL7737292 | 0.76 | SLC5A2 (0.39) | HTR6KMT2AMEN1GAACHRM1 | |
| SCHEMBL7737187 | 0.73 | HTR6 (0.41) | HTR6CHRM1DRD2HTR2AMCHR1 | |
| SCHEMBL19682942 | 0.70 | PKM (0.44) | HTR6GAACHRM1CHRM2LTA4H | |
| SCHEMBL7730055 | 0.69 | ALOX12 (0.58) | KMT2AMEN1GAARECQLALDH1A1 | |
| SCHEMBL14139251 | 0.68 | KMT2A (0.51) | KMT2AMEN1GAACHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202084-C | Fused benzene heterocycle derivatives and utilization thereof | TORAY INDUSTRIES (JP) | 2005-05-18 | — | — | CN | disclosed |
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| CN-1287553-A | Fused benzene heterocycle derivatives and utilization thereof | TORAY INDUSTRIES (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |