Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.49 |
| ▸ | FNTB | P49356 | 19/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743701 | 0.87 | CYP11B1 (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8483628 | 0.86 | CYP11B1 (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7744106 | 0.86 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2CYP11B1 | |
| Hydrochloric Acid SCHEMBL7746020 | 0.85 | FNTA (0.59) | FNTAFNTBPGGT1BKCNH2CYP11B1 | |
| SCHEMBL8480547 | 0.80 | FNTA (0.58) | FNTAFNTBPGGT1BKCNH2CYP11B1 | |
| Hydrochloric Acid SCHEMBL7744123 | 0.80 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2CYP11B1 | |
| SCHEMBL7743768 | 0.71 | FNTA (0.66) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL10101653 | 0.71 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7738189 | 0.70 | FNTA (0.64) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL694505 | 0.69 | PARP1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045843-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-10-24 | — | — | EP | claimed |
| EP-1045843-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-10-25 | — | — | EP | claimed |
| WO-1999028313-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-06-10 | — | — | WO | claimed |
| EP-1045843-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-1045843-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028313-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-06-10 | — | — | WO | disclosed |