Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738438 | 0.81 | EGFR (0.36) | EGFRPIK3CDPIK3CA | |
| SCHEMBL30432091 | 0.78 | EGFR (0.47) | EGFRPIK3CDPIK3CA | |
| SCHEMBL1096307 | 0.78 | EGFR (0.47) | EGFRPIK3CDPIK3CA | |
| SCHEMBL17511928 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL9872273 | 0.69 | LMNA (0.65) | EGFRPIK3CDPIK3CA | |
| SCHEMBL4424448 | 0.68 | EGFR (0.43) | EGFRPIK3CDPIK3CA | |
| SCHEMBL11405666 | 0.68 | EGFR (0.40) | EGFRPIK3CDPIK3CA | |
| SCHEMBL9676827 | 0.67 | LMNA (0.38) | EGFRPIK3CDPIK3CA | |
| SCHEMBL9445068 | 0.67 | EGFR (0.35) | EGFRPIK3CDPIK3CA | |
| SCHEMBL157707 | 0.66 | EGFR (0.35) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |