Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | FNTA | P49354 | 1/20 | 0.61 |
| ▸ | FNTB | P49356 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyphenyl Propionic Acid SCHEMBL7727271 | 0.94 | CA2 (0.76) | FFAR1CA2CAMK2AKEAP1FNTA | |
| Phenyl Propionic Acid SCHEMBL10575939 | 0.91 | KEAP1 (0.83) | FFAR1KEAP1AKR1B1FFAR4ALDH1A1 | |
| Phenylacetic Acid SCHEMBL29388435 | 0.89 | CA2 (0.86) | FFAR1CA2CAMK2AFNTAFNTB | |
| Phenyl Propionic Acid SCHEMBL27725915 | 0.87 | KEAP1 (0.83) | FFAR1KEAP1FFAR4TRPV1ALDH1A1 | |
| Hydroxyphenyl Propionic Acid SCHEMBL35486 | 0.87 | FFAR1 (0.68) | FFAR1CA2CAMK2AKEAP1FFAR4 | |
| SCHEMBL28953591 | 0.87 | FFAR1 (0.68) | FFAR1CA2CAMK2AKEAP1AKR1B1 | |
| SCHEMBL11318819 | 0.87 | FFAR1 (0.68) | FFAR1CA2CAMK2AKEAP1AKR1B1 | |
| Hydroxyphenyl Propionic Acid SCHEMBL5606896 | 0.85 | FFAR1 (0.65) | FFAR1CA2CAMK2AKEAP1FFAR4 | |
| Hydroxyphenyl Propionic Acid SCHEMBL10712090 | 0.85 | FFAR1 (0.65) | FFAR1CA2CAMK2AKEAP1FFAR4 | |
| Hydroxyphenyl Propionic Acid SCHEMBL18263865 | 0.85 | FFAR1 (0.65) | FFAR1CA2CAMK2AKEAP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6409937-B1 | 4-HYDROXYPHENYLACETIC ACID, 3-(4-HYDROXYPHENYL)PROPIONIC ACID, TEREPHTHALIC ACID, HYDROQUINONE, 2,6-NAPHTHALENE DIOL, 4,4'-BIPHENOL; ACETYLATION, HYDROLYSIS AT REDUCED PRESSURE FOR EFFICIENT ACETIC ACID REMOVAL AND HIGHER MOLECULAR WEIGHT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-06-25 | — | — | US | claimed |