Hydroxyphenyl Propionic Acid

Hydroxyphenyl Propionic Acid

SCHEMBL35486

O=C(O)CCc1ccc(O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 8/20 0.68
KEAP1 Q14145 1/20 0.67
CA2 P00918 2/20 0.60
CAMK2A Q9UQM7 1/20 0.60
ESR1 P03372 2/20 0.59
ESR2 Q92731 1/20 0.59
FFAR4 Q5NUL3 2/20 0.57
CA1 P00915 1/20 0.57
CYP19A1 P11511 2/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
KDM4E B2RXH2 1/20 0.55
MEN1 O00255 1/20 0.55
SLC16A3 O15427 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
TTR P02766 1/20 0.55
TP53 P04637 1/20 0.55
CYP1A2 P05177 1/20 0.55
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyphenyl Propionic Acid SCHEMBL5606896 0.98 FFAR1 (0.65) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL10712090 0.98 FFAR1 (0.65) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL28184441 0.98 FFAR1 (0.65) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL18263865 0.98 FFAR1 (0.65) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL28123368 0.96 FFAR1 (0.63) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL7727261 0.94 FFAR1 (0.61) FFAR1KEAP1CA2CAMK2AESR1
SCHEMBL3293457 0.94 FFAR1 (0.74) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL10765619 0.92 L3MBTL1 (0.59) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL7727271 0.92 CA2 (0.76) FFAR1KEAP1CA2CAMK2AESR1
Hydroxyphenyl Propionic Acid SCHEMBL2523914 0.92 HDAC3 (0.64) FFAR1KEAP1CA2CAMK2AHDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6224 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350131-B Method for preparing phenolic chemicals by catalytic lignin transfer hydrogenolysis of cobalt-based nitrogen-carbon composite material SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-122011356-A Biodegradable anti-aging agent and preparation method and application thereof 北京工商大学 2026-05-12 CN claimed
US-12611439-B2 Ionic self-assembling peptides 3-D MATRIX, LTD. (JP) 2026-04-28 US claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4701444-A1 NUTRITIONAL COMPOSITION Société des Produits Nestlé S.A. (CH) 2026-03-04 EP claimed
WO-2026044024-A1 COMPOSITIONS COMPRISING COMBINATIONS OF PHARMACEUTICALLY ACCEPTABLE SALTS AND OTHER DERIVATIVES OF GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND PHARMACEUTICALLY ACCEPTABLE SALTS AND OTHER DERIVATIVES OF AMYLIN ANALOG, AND USES THEREOF I2O THERAPEUTICS, INC. (US) 2026-02-26 WO claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2025129053-A1 METHODS AND COMPOSITIONS FOR BIOPRODUCTION OF PHLOROGLUCINOL Debut Biotechnology, Inc. (US) 2025-06-19 WO claimed
CN-120158416-A Method for culturing multicellular spheroids based on hydrogel structural material, multicellular spheroid composition and application 深圳先进技术研究院 2025-06-17 CN claimed
WO-2025122010-A1 A METHOD FOR PURIFYING A MODIFIED GELATIN SENTRYX B.V. (NL) 2025-06-12 WO claimed
EP-0115885-A1 Stabilized polymer composition STAMICARBON B.V. (NL) 1984-08-15 EP claimed
US-4463102-A Polyolefin polymerization catalyst containing sterically unhindered phenolic compounds (II) NORTHERN PETROCHEMICAL COMPANY (US) 1984-07-31 US claimed
US-4354018-A ACTIVATION WITH THIONYL CHLORIDE TO FORM POLYLACTONE MICHIGAN MOLECULAR INSTITUTE (US) 1982-10-12 US claimed
WO-1982001301-A1 MECHANISM FOR DE-REPRESSION CONTROL SAMPSON MICHAEL J 1982-04-29 WO claimed
EP-0050504-A1 Mechanism for de-repression control Sampson, Michael James (GB) 1982-04-28 EP claimed
US-4254095-A GLYCOPROTEIN HORMONE-ANTIGEN COMPLEX LABELLED FOR USE AS TRACER N KIT FORM RESEARCH CORPORATION (US) 1981-03-03 US claimed
US-4075146-A A PHENOLIC ANTIOXIDANT DART INDUSTRIES, INC. (US) 1978-02-21 US claimed
US-4049751-A POLYMERIC NITROGENOUS COMPLEXING AGENT FOR PHENOLIC ANTIOXIDANT ON DART INDUSTRIES INC. (US) 1977-09-20 US claimed
US-4021535-A Reagents used in the radioimmunoassay of digoxin BECKMAN INSTRUMENTS, INC. (US) 1977-05-03 US claimed
US-3951911-A Stabilized propylene-based polymer compositions DART INDUSTRIES INC. (US) 1976-04-20 US claimed